perspective lectures – wissenschaftliche Vortragsreihe

perspective lectures – wissenschaftliche Vortragsreihe

Die perspective lectures sind eine öffentliche Vortragsreihe der Universitätsklinik der Johann Wolfgang Goethe-Universität Frankfurt und des Gesundheitsunternehmens Sanofi, zu der führende Wissenschaftler*innen und herausragende Persönlichkeiten als Vortragende eingeladen werden.

Die Vorträge haben zum Ziel, innovative Forschung zu präsentieren und Perspektiven aufzuzeigen, wie Wissenschaftler*innen die Zukunft unserer Gesellschaft positiv gestalten können. Die perspective lectures sollen so den wissenschaftlichen und öffentlichen Diskurs über die maßgeblichen Felder aus Wissenschaft und Forschung anregen.

perspective lectures: öffentliche Vortragsreihe der Universitätsklinik der Johann Wolfgang Goethe-Universität Frankfurt und des Gesundheitsunternehmens Sanofi

Die nächsten perspective lectures

Datum Veranstaltung Ort
18:15 Uhr

Moritz Helmstaedter
Max Planck Institute for Brain Research Department of Connectomics, Frankfurt
Access information for the online lecture will be provided after registration.
To register, please send an e-mail to:
18:15 Uhr

Maya Schuldiner
Weizmann Institute of Sciences, Dept. Of Molecular Genetics, Rehovot, Israel
»Titel wird noch bekanntgegeben»
Klinikum der Johann Wolfgang Goethe-Universität, Hörsaalgebäude 20 – 5, Audimax, Theodor-Stern-Kai 7, Frankfurt
Frühjahr 2022

Luca Scorrano
Venetian Institute for Molecular Medicine, Department of Biology, Padova, Italy
»Keeping Mitochondria in Shape, a Matter of Life, Death and Metabolism»
Klinikum der Johann Wolfgang Goethe-Universität, Hörsaalgebäude 23-3, Gebäude 23, Campus Niederrad, Theodor-Stern-Kai 7, Frankfurt



Goethe Universität,
Theodor-Stern-Kai 7,
D-60596 Frankfurt am Main

Übersichtsplan des Universitätsklinikums Frankfurt


Prof. Dr. Ivan Dikic
Institut für Biochemie II
Universitätsklinikum Frankfurt / Gebäude 75
Sandhofstrasse 2-4
60528 Frankfurt am Main
✆  069-6301-5652   ✉

Dr. Karl-Heinz Baringhaus
Sanofi-Aventis Deutschland GmbH
Frankfurt am Main

Rückblick auf bisherige perspective lectures

Datum Veranstaltung Link

Matthew Disney
The Scripps Research Institute, Department of Chemistry, Jupiter, FL, USA
»Sequence-based Design of Small Molecules Targeting RNA Structures to Manipulate and Study Disease Biology»

Matthew Disney
im Internet
25.11.2021 Andrea Musacchi
Max Planck Institute of Molecular Physiology, Dortmund
»The Kinetochore, an Intrinsically Divisive Molecular Machine»
Andrea Musacchi
im Internet
14.06.2021 Jared Rutte
Howard Hughes Medical Institute, University of Utah, USA
»Metabolism, Cellular Decisions and the Language that Unites Them»
Jared Rutte
im Internet
06.05.2021 Prof. Dr. Feng Shao
National Institute of Biological Sciences, Beijing, China
»Pyroptosis, Inflammation and Antitumor Immunity»
Prof. Dr. Feng Shao
im Internet
22.04.2021 Richard Morimoto
Northwestern University, Evanston, USA
»The Biology of Proteostasis and the Heat Shock Response in Aging and Disease»
Richard Morimoto
im Internet
14.01.2021 Michael Rapé
University of California, Berkeley, USA
»Development under Stress: Novel Quality Control Pathways in Human Development and Disease»
Michael Rapé
im Internet
03.12.2020 Anu Wartiovaara
University of Helsinki, Biomedicum Helsinki, Helsinki, Finland
»Why Diseases are Tissue-Specific? Lessons from Mitochondrial Diseases and Implications for Therapy»
Anu Wartiovaara
im Internet
03.11.2020 Martin Beck
Max-Planck-Institute for Biophysics, Frankfurt, Germany
»Solving a 3D jigsaw with 1000 pieces – Structure, assembly and turnover of the nuclear pore complex»
Martin Beck
im Internet
21.10.2019 Jacob Corn
ETH Zürich, Switzerland
»CRISPR-Cas Genome Editing at Work in Human Cells»
Jacob Corn
im Internet
02.07.2019 Reinhard Jahn
Max Planck Institute for Biophysical Chemistry, Goettingen, Germany
»Membrane Traffic in Endosomes – How is Targeting Specificity Achieved?»
Reinhard Jahn
im Internet
16.05.2019 Wade Harper
Department of Cell Biology, Harvard Medical School, Boston, MA, USA
»Role of Selective Autophagy in Cellular Homeostasis and Neurodegenerative Disease»
Wade Harper
im Internet
16.05.2019 Brenda Schulman
Department of Molecular Machines and Signaling, MPI of Biochemistry, Martinsried, Germany
»Ubiquitin and Mitosis: Regulation by a Molecular Machine»
Brenda Schulman
im Internet
13.02.2019 Prof. Dr. Vivek Malhotra
Centre for Genomic Regulation, Barcelona, Spain
»Building a Machine for Secretion of Bulky Collagens from Endoplasmic Reticulum»
Vivek Malhotra
im Internet
12.12.2018 Prof. Dr. Roland Lill
Institut für Zytobiologie, Philipps Universität Marburg, Germany
»Biogenesis of Iron-Sulfur Proteins in Eukaryotes: A Complex Pathway for many Different Dellular Functions»
Roland Lill
im Internet
03.12.2018 Tony Hyman
Max Planck Institute of Molecular Cell Biology & Genetics, Dresden, Germany
»Biomolecular Condensates and their Implications for Physiology and Disease»
Tony Hyman
im Internet
25.10.2018 Man-Wah Tan
Genentech Inc., Infectious Diseases Department,
South San Francisco, CA
»Inspired by Nature: Engineering Natural Products and Antibodies to Treat Bacterial Infections»
Man-Wah Tan
im Internet
09.04.2018 Erika Holzbaur
Perelman School of Medicine, University of Pennsylvania,
Philadelphia, USA
»Autophagy dynamics in neuronal homeostasis and neurodegeneration»
Erika Holzbaur
im Internet
21.02.2018 Andrea Ballabio
Telethon Institute of Genetics and Medicine (TIGEM),
Naples, Italy
»The Awesome Lysosome»
Andrea Ballabio
im Internet
01.12.2017 Claudio Joazeiro
Center for Molecular Biology (ZMBH), University Heidelberg
Heidelberg, Germany
»Ribosome-Associated Protein Quality Control (RQC) and Neurodegeneration»
Claudio Joazeiro
im Internet
17.11.2017 Trey Ideker
University of California San Diego (UCSD), School of Medicine, La Jolla, CA, USA
»Active Interaction Mapping Reveals the Hierarchical Organization of Autophagy»
Trey Ideker
im Internet
26.10.2017 René Bernards
The Netherlands Cancer Institute (NKI), Amsterdam,
The Netherlands
»Finding new vulnerabilities of cancer cells for therapeutic benefit»
René Bernards
im Internet
25.04.2017 Tamotsu Yoshimori
Department of Genetics, Osaka University,
Osaka, Japan
»Insights into membrane dynamics of autophagy and its implications in diseases»
Tamotsu Yoshimori
im Internet
07.12.2016 Dario Alessi
MRC Protein Phosphorylation and Ubiquitylation Unit, College of Life Sciences, University of Dundee, 
Dundee, UK
»Disruptions on the Highways of Cellular Signalling»
Dario Alessi
im Internet
12.10.2016 Ralph Nixon
Department of Psychiatry, NYU School of Medicine,
New York, USA
»The Pathogenic Role of Defective Endosomal-Lysosomal Function in Alzheimer’s Disease»
Ralph Nixon
im Internet
01.06.2016 Joan Massagué
Memorial Sloan Kettering Cancer Center,
»Metastatic Colonization by Circulating Tumor Cells»
Joan Massagué
im Internet
03.05.2016 Dirk Bumann
Biozentrum Basel, University of Basel,
»Pathogen Eterogeneity during Infection: Impact on Disease Progression and Therapy»
Dirk Bumann
im Internet
11.12.2015 Sharon Tooze
The Francis Crick Institute,
London, UK
»Regulation of Autophagosome Formation in Mammalian Cellsnity»
Sharon Tooze
im Internet
03.07.2015 Tadatsugu Taniguchi
Institute of Industrial Science, The University of Tokyo
Tokyo, Japan
»Recognition of Self-Derived Molecules in the Regulation of Inflammation and Anti-Tumor Immunity«
Tadatsugu Taniguchi
im Internet
08.06.2015 David Vaux
Institute of Medical Research, Walter and Eliza Hall
Melbourne, Australia
»Targeting IAP and Bcl-2 family proteins to treat cancer»
David Vaux
im Internet
05.05.2015 Wolfgang Baumeister
Max Planck Institute of Biochemistry, Structural Cell Biology Department
Martinsried, Germany
»Electron Cryomicroscopy and Cellular Pathology»
Wolfgang Baumeister
im Internet
13.03.2015 James P. Allison
The University of Texas MD Anderson Cancer Center
Houston, TX, USA
»Immune Checkpoint Blockade in Cancer Therapy:  New Insights, opportunities and prospects for a Cure»
James P. Allison
im Internet
18.11.2014 Elena Conti
Max Planck Institute of Biochemistry
Martinsried, Germany
»The Exosome Complex in RNA Processing and Decay»
Elena Conti
im Internet
13.05.2014 K. C. Nicolaou
Department of Chemistry, Rice University
Houston, TX, USA
»Total Synthesis of Rare Natural and Designed Molecules of Biological and Medical Importance» 
K. C. Nicolaou
im Internet
29.04.2014 Volker Haucke
Leibniz-Institut für Molekulare Pharmakologie
Berlin, Germany
»Spatiotemporal Control of Endocytosis - from Mechanisms to Synaptic Function» 
Volker Hauke
im Internet
12.03.2014 Michael Reth
Max Planck Institute of Immunobiology and Epigenetics, University of Freiburg, Germany
»Sensing the Unknown for Antibody Production: From the Side Chain Theory to the Dissociation Activation Model»
Michael Reth
im Internet
22.10.2013 Susan Lindquist
Whitehead Institute for Biomedical Research,
Nine Cambridge Center, Massachusetts, USA
»A rapid discovery platform for protein folding diseases»
02.09.2013 Randy Schekman
Li Ka Shing Center, UC Berkeley, CA, USA
» Cargo Sorting into Transport Vesicles: Mechanism and Relation to Mammalian Development »
Randy Schekman
im Internet
16.04.2013 Eric N. Olson
Department of Molecular Biology
UT Southwestern Medical Center at Dallas, USA
»The Molecules and Mechanisms of Heart Development, Disease and Regeneration »
Eric N. Olson
im Internet
05.03.2013 Rüdiger Klein
Max-Planck-Institut für Neurobiologie, München-Martinsried, Deutschland
» Molecular Principles of Axon Guidance »
Rüdiger Klein
im Internet
22.05.2012 Ron Breaker
Department of Molecular, Cellular and Developmental Biology,
Yale University, New Haven Rolf Sammet Stiftungsprofessor 2012
Antibiotics and Riboswitches
Ron Breaker
im Internet
13.03.2012 Peter Walter
Department of Biochemistry & Biophysics, University of California, San Francisco
» The Unfolded Protein Response
in Health and Disease «
Peter Walter
im Internet
07.02.2012 Reinhard Jahn
Max-Planck-Institut für biophysikalische Chemie Göttingen, Deutschland
» Signalling between Neurons –
How Nerve Cells speak to each other »
Reinhard Jahn
im Internet
08.11.2011 Axel Ullrich
Max-Planck-Institut für Biochemie Martinsried, Deutschland
» 30 Years of Molecular Medicine: Oncogenomics towards Novel Cancer Therapies «
Axel Ullrich
im Internet
20.09.2011 Raymond J. Deshaies
Howard Hughes Medical Institute, Pasadena, CA, USA
» Mechanisms and Regulation of
Cullin-RING Ubiquitin Ligases »
Raymond J. Deshaies
im Internet
24.05.2011 Ronald M. Evans
La Jolla, CA, USA
Rolf Sammet-Stiftungsprofessur 2011 der Aventis-Foundation
» Nuclear Receptors and AMPK – Resetting Metabolism «
Ronald M. Evans
im Internet
25.01.2011 Jennifer Lippincott-Schwartz
National Institute of Child Health and Human Development,
National Institute of Health Bethesda, MD, USA
» Seeing Cells in Action with
Photoactivatable Fluorescent Proteins «
Jennifer Lippincott-Schwartz
im Internet
16.11.2010 Franz Ulrich Hartl
Max-Planck-Institut für Biochemie,
Abt. Zellulaere Biochemie, Martinsried
» Chaperone-assisted protein folding in health and disease «
Franz Ulrich Hartl
im Internet
21.09.2010 Sir Tim Hunt
London Research Institute
» New Elements in the Control of Mitosis: Fresh Light on Protein Phosphatases «
Sir Tim Hunt
im Internet
06.07.2010 Edmond H. Fischer
Department of Biochemistry,
University of Washington, Seattle, WA, USA
» The Origin of Reversible Phosphorylation «
Edmond H. Fischer
im Internet
19.05.2010 C. Ronald Kahn
Joselin Diabetes Center and Harvard Medical School, Boston, USA
» Critical Nodes in Insulin Action and Insulin Resistance «
C. Ronald Kahn
im Internet
10.02.2010 Inder M. Verma
Salk Institute for Biological Studies, La Jolla, USA
» Cancer: A Malady of Genes «
Inder M. Verma
im Internet
17.11.2009 Sir Philip Cohen
Scottish Institute for Cell Signalling
College of Life Science, University of Dundee, UK
» The Interplay between Protein Phosphorylation and Protein Ubiquitylation in Regulating the Innate Immune System «
Sir Philip Cohen
im Internet
23.06.2009 Venki Ramakrishnan
MRC Laboratory of Molecular Biology, Cambridge, UK
» Induced fit: A common strategy used by the Ribosome «
Venki Ramakrishnan
im Internet
20.03.2009 Susumu Tonegawa
Massachusetts Institute of Technology
Nobel Prize Medicine/Physiology 1987
» Neural Mechanisms for Memory «
Susumu Tonegawa
im Internet
12.03.2009 Elizabeth Blackburn
Department of Biochemistry and Biophysics University of California, San Francisco, USA
Paul Ehrlich- und Ludwig Darmstädter Preisträgerin 2009
» Responses of Cells and Organisms to Perturbing Telomere Maintenance «
Elizabeth Blackburn
im Internet
10.02.2009 Pascale Cossart
Dept. Cell Biology and Infection, Institut Pasteur, Paris
» The Bacterial Pathogen Listeria monocytogenes: the Rise of a Multifaceted Model «
Pascale Cossart
im Internet
25.11.2008 Edward Dennis
University of California San Diego, USA
» Eicosanoid Lipidomics and Phospholipase A2
Role in Inflammatory Disease «
Edward Dennis
im Internet
18.11.2008 Peter Walter
University of California San Francisco, USA
» Protein Homeostasis in Health and Disease «
Peter Walter
im Internet
24.09.2008 Anthony J. Pawson
Samuel Lunenfeld Research Institute, Mt Sinai Hospital, Toronto, Canada
» SH2 domains and tyrosine kinases - back to the future «
Anthony J. Pawson
im Internet
14.03.2008 Tim Mosmann
Center for Vaccine Biology and Immunolgy, University of Rochester, NY, USA
» Significance of T Cell Diversity in Immune Responses «
Tim Mosmann
im Internet
03.03.2008 Hidde Ploegh
Whitehead Institute for Biomedical Research, Cambridge, USA
» Herpesviruses as Tools: Antigen Presentation and Protein Quality Control «
Hidde Ploegh
im Internet
22.01.2008 Josef Penninger
Institute of Molecular Biotechnology, Vienna, Austria
» From Systems Genetics in Flies to Human Medicine «
Josef Penniger
im Internet
27.11.2007 Garret A. FitzGerald
Dept. of Pharmacology, University of Pennsylvania School of Medicine, USA
» Therapeutic Adventures in the Arachidonic Acid Cascade «
Garret A. FitzGerald
im Internet
13.11.2007 Matthias Kleiner
Präsident der Deutschen Forschungsgemeinschaft, Bonn
» Wissenschaft im Wettbewerb «
Matthias Kleiner
im Internet
05.06.2007 Peter Mombaerts
The Rockefeller University, New York
and Max-Planck-Institute of Biophysics, Frankfurt
» Olfaction targeted «
Peter Mombaerts
im Internet
14.03.2007 Harry F. Noller
Center for Molecular Biology of RNA, Sinsheimer Laboratories University of California - Santa Cruz, USA
» Ribosome Structure and Dynamics: Caught in the Act «
Harry F. Noller
im Internet
09.11.2006 Anthony Cerami
Warren Pharmaceuticals, Inc, Ossining, NY, USA
» TNF and Erythropoietin: The Lucifer and Gabriel Cytokine «

Charles Dinarello
University of Colorado School of Medicine, Denver CO
» Fever, Interleukin-1 and the Beginning of Cytokine Biology «
Anthony Cerami
im Internet

Charles Dinarello
im Internet
19.09.2006 Aaron Ciechanover
Israel Institute of Technology, Haifa
» The Ubiquitin Proteolytic System - from a Vague Idea, through Basic Mechanisms and onto Human Diseases and Drug Targeting «
Aaron Cienachover im Nobel e-Museum
23.05.2006 Roderick MacKinnon
» Structure and Function of Potassium Channels (K+) «
Rockefeller University/HHMI New York
Roderick MacKinnon im Internet
14.03.2006 Craig Mello
Howard Hughes Medical Institute, University of Massachusetts, Worcester
» RNAi and Development in C. elegans «
Craig Mello im Internet
24.01.2006 Hans Clevers
University of Utrecht, NL
» Wnt and Notch Signaling Pathways in Development and Cancer of the Gut «
Hans Clevers im Internet
13.12.2005 Chris Dobson
University of Cambridge
» Protein Misfolding and Human Disease «
Chris Dobson im Internet
05.07.2005 Adam Smith
Nature Publishing Group
» Role of Publishing at the Intersection of Academic and Industrial Science «
12.04.2005 Rudolf Jaenisch
Whitehead Institute for Biomedical Research, Cambridge
» Nuclear Cloning, Stem Cells and Genomic Reprogramming «
Rudolf Jaenisch im Internet
08.02.2005 Jean-Marie Lehn
University Louis Pasteur, Strasbourg
» Some Contributions of Supramolecular Chemistry to Life Sciences «
Jean-Marie Lehn im Internet
14.12.2004 Kai Simons
Max-Planck-Institute for Molecular Cell Biology and Genetics, Dresden
» Lipid Rafts: An Organizational Principle in Cell Membranes «
Kai Simons im Internet
06.07.2004 Klaus Rajewsky
Harvard Medical School, Center for Blood Research, Boston
» Modeling Human Diseases in the Mouse «
– on this and the Other Side of the Atlantic –
Klaus Rajewsky
im Internet
18.05.2004 Joseph Schlessinger
Yale University School of Medicine, New Haven CT
» Cell Signaling by Tyrosine Phosphorylation:
From the Bench to the Bedside «
Joseph Schlessinger
im Internet
20.04.2004 Tony Hunter
The Salk Institute for Biological Studies, La Jolla
» The Many Roles of Protein Phosphorylation
in Cellular Signaling «
Tony Hunter im Internet
29.01.2004 Thomas R. Cech
Howard Hughes Medical Institute, University of Colorado, Boulder
» Interdisciplinary Science for the 21st Century:
The Howard Hughes Medical Institute«
Thomas R. Cech im Internet
09.12.2003 Peter Carmeliet
Flanders Universität, Leuven (Belgien)
» Genetics in Mice, Zebrafish and Humans to Unravel Angioge-nesis: Therapeutic Perspectives «
Peter Carmeliet im Internet
08.07.2003 Salvador Moncada
The Wolfson Institute for Biomedical Research, London
» Nitric Oxide and Cell Respiration:
Physiology and Pathophysiology «
Salvador Moncada
im Internet
13.05.2003 Helen Blau
Stanford Universität, Palo Alto
» Marrow-associated Stem Cells for Brain and Brawn «
Helen Blau im Internet
14.03.2003 Richard Lerner
Scripps Research Institute, La Jolla
» Antibody Catalysis, Ozone, and Atherosclerosis: New Aspects of the Immune System«
Richard Lerner im Internet
11.02.2003 Marco Baggiolini
Università della Svizzera Italiana, Lugano (Schweiz)
» Little, Big Chemokines: From Regulation of Leukocyte Traffic to Therapy of Inflammatory Diseases «
Marco Baggiolini im Internet
14.01.2003 Svante Pääbo
Max-Planck-Institut für Evolutionäre Anthropologie, Leipzig
» An Ape Perspective of Human Uniqueness «
Svante Pääbo im Internet
03.12.2002 Konrad Beyreuther
ZMBH Heidelberg
» Ageing without Alzheimer «
Konrad Beyreuther im Internet
15.10.2002 Karl Einhäupl
Neurologische Klinik, Charité, Berlin
Vorsitzender des Wissenschaftsrats
» Hochschulmedizin: zwischen Spitzenforschung und Massenuniversität? «
Karl Einhäupl im Internet
09.07.2002 Robert Huber
Max-Planck-Institut für Biochemie, München
» Molecular Machines for Protein Degradation «
Robert Huber im Internet
23.04.2002 Günter Blobel
Rockefeller Universität, New York
» Protein Targeting «
Günter Blobel im Internet